Nадеюсь, Вы придёте к правильному решению. Не отчаивайтесь.
{there are|exist|happen|occur} {also} concerns about the {effectiveness|efficiency|efficacy} and {harmlessness|safety} of some #file_links<>C:UsersAdminDesktopfilegsa+en+PBN70T2k10kGeorgiy1705252P2URLBB.txt",1,N], especially {those|all} that {but they} have not {{been|turned into} thoroughly tested in clinical trials.