Interestingly, riboflavin enhanced the effect of 400 Оg folic acid on circulating 5 methyltetrahydrofolate 5 MTHF specifically in the polyp patients with the C677T genetic variant 45 priligy 30mg 59 60 Most patients improve symptomatically even without marked postoperative changes in left ventricular mass or volume or improvement in left ventricular systolic function