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@Luu ~u~yu  Simades 19/8/11() 16:11

@
@薼 F Luu ~u~yu
@O F Simades <simaland6@gmail.com>
@t F 19/8/11() 16:11
@v F https://anticancer24.ru/shop/103/desc/xalkori
@-------------------------------------------------------------------------

   Xq r|uy p{, uqu tsuu y u{yr~u 

|uu~yu. 

Muty{p}u~ Kp|{y (Crizotinib) - Xalkori (Kyxy~yq) 

ut~px~pu~ t| upyy ~u}u|{{|u~s p{p |vs{y. Nruzuu utr u| |y~ xpu{}u~trp uq r upyy uvx~s xpq|urp~y. 

 

Rpr y rzrp 

B u{yr~z upp |ut~us {|u~y rty p{yr~u 

|u{pru~~u ruur {yxy~yq, {u r|u 

u|u{yr~} y~syqy} yxy~{y~px y {y~px p~p|pyu{z 

|y}}. 

Sp{wu r upp r{|u~ t|~yu|~u ruurp, 

{u qr |uz pqqyy |u{pru~~s 

ruurp. 

Lu{pr |ut~us {|u~y u{ppu tp|~uzuu pxryyu 

x|{puru~~z |y y qyrpu p{ru {|u{y. 

B ux|pu rxtuzry utrp yty y~tyrp~yu 

{yxy~yq} |ur {|u~ {. 

Pupp Kp|{y@}~u yr|uru utr, 

{u p ~px~ppu rpp}y, u|y uttuu |uu~yu 

p{p |vs{y ~u y~u| |wyu|~s ux|pp. 

Pyr|uru rxtuzryu utrp r|u txxpryy}}. 

Xq }uty{p}u~ 

Kp|{y (Crizotinib) - Xalkori (Kyxy~yq) {y  ~ywu~~z u~u, qppzu r ~p y~u~u pu{. 

 

P{pxp~y 

 ALK-xyyr~z ~u}u|{{|u~z p{;@ROS-1-xyyr~z p{ |vs{s. 

 

Pyr{pxp~y 

 syurryu|~ { pr utrp;@quu}u~~;@|p{py;@tu{yz rxp; 

 uv~~p ~utp~;@r}u~z yv}  y~syqyp}y CYP3A. 

 

Rq y}u~u~y 

Pyv} tp~~s |u{prp ~u xpryy  uq|u~y yy. Kp|p s|prpu, 

~u pxwvrrp. Suqu ~uu}u~~ xpy }uty{p}u~ yz rtz. 

Muty{y u{}u~t tx uppp - 250 }s (2 pxp r {y). 

Nu |utu trpyrp |u{pru~~ txyr{ y {u uq|u~y utrp. 

Ku{y tx xpryy  rpwu~~y CTCAE. 

Py rpwu~~ q~ u{p |u{pr ru}u~~ }u~u. 

Ot~p{ ~p utr Kp|{y (Crizotinib) - Xalkori (Kyxy~yq) xr 

rup |y |wyu|~u. Pupp  uu~y sp~yx}}. 

 

Pq~u up{yy 

 s|r{wu~y;@~uzpy;@~ywu~yu puyp;@~p;@typu;@xp; 

 ~pu~y xu~y. 

 

Ctu {y |u{pr 

T ~p ~p pzu {pwtz {pu| }wu {y |u{pr  yu}|u}z y}y. 

Np }uty{p}u~ Kp|{y (Crizotinib) - Xalkori (Kyxy~yq) u~p t~p {pwt} 

{pu|. B }wuu xp{pxp tpr{ }uty{p}u~p  {pxp~~} ~}u u|u~p |yq 

}y {{ } r }u xp{pxp. E|y rp} uqu |u{pr 

Kp|{y (Crizotinib) - Xalkori (Kyxy~yq) y} r ~puz y~u~u pu{u 

~p}~s ~ywu, u} r tsy ~{p tpwy. Pyquu~yu }uty{p}u~p ~p ~pu} 

pzu spp~yu rp} r{u {pur ~w~s |u{prp y {~}y tu~us. 

B }wuu xp{pxp ~uqty}u |u{pr, ~u rt yx t}p, } uzp!





{p|{y 250 y}u~u~yu + tuuz xr


				  


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